Well for various reasons it has been a little while since our last post but we’re back with a review of a paper that was looked at during our more recent local journal club. The paper is entitled ‘Adequate antibiotic admission prior to ICU admission in patients with severe sepsis and septic shock reduces hospital mortality’ and is freely available via the link below, so definitely worth having a bit of a look at. Sepsis is probably the top condition we face in critical care, and indeed probably for hospital medicine as a whole. There have been big strides forward in the management of this massive killer, though we still seem a little way off understanding this very diverse condition completely. The triad of ARISE, PROMISE and PROCESS have expanded how we think about the resuscitation for the condition, but one of the lynchpins of treatment has always been early antibiotics. Indeed I think some of the numbers from Kumar et al.’s have been extrapolated to every infection through the widespread education of the Sepsis 6 (I don’t think my patient with a simple UTI will have a 7% increase in mortality from an hour delay in antibiotics, but the message is pretty widespread at least). So I was quite interested to see what this particular paper could provide in the way of improved understanding.
Adequate antibiotic admission prior to ICU admission in patients with severe sepsis and septic shock reduces hospital mortality
Adequate antibiotic admission prior to ICU admission in patients with severe sepsis and septic shock reduces hospital mortality
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